NIH Conference and Legislative Update

…Workshop, please go to http://www.sonicfoundry.com/NIH. With regard to the SMA Treatment Acceleration Act, despite our best efforts and the unbelievable show of support by families across the nation, the current…

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Drug Development Process

…The goal of lead optimization is to identify a compound (Development Candidate) suitable for preclinical development. Preclinical Development: This stage consists of testing a Development Candidate in various in vitro…

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Drug Discovery

…vitro systems to screen existing drugs and compound libraries. Over 120 such compounds were screened in mouse models of severe SMA, but none produced more than a modest effect on…

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SMA Journal Articles

Research: SMA Journal Articles Research: SMA Journal Articles A selection of recent articles in the field of SMA is provided below. For a complete listing of SMA research articles, please…

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